TK216
Catalog No.
BA3968
TK216 is an orally potent inhibitor of the E26 transcription factor.
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TK216 is an orally potent inhibitor of the E26 transcription factor.TK216 directly binds to EWS-FLI1 and inhibits EWS-FLI1 protein interactions.TK216 prevents EWS-FLI1 from binding to RNA deconjugating enzyme A.TK216 has anticancer activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 376.23 |
| Cas No. | 1903783-48-1 |
| Formula | C19H15Cl2NO3 |
| Solubility | ≥52.1 mg/mL in DMSO; ≥17 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | 4,7-dichloro-3-(2-(4-cyclopropylphenyl)-2-oxoethyl)-3-hydroxyindolin-2-one |
| Canonical SMILES | O=C1NC2=C(C(Cl)=CC=C2Cl)C1(CC(C3=CC=C(C4CC4)C=C3)=O)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
