Tiapride Hydrochloride

Tiapride Hydrochloride (CAS No.: 51012-33-0) is a synthetic small molecule dopamine receptor antagonist in the substituted benzamide research class, broadly categorized as a neuropharmacology tool compound for investigating dopaminergic regulation in central nervous system biology, with primary activity at D2 like and D3 dopamine receptors and reported in vitro potency in the nanomolar range, making it suitable for mechanistic studies of receptor mediated signaling, neurotransmission balance, and behavior related pharmacology in preclinical systems; functionally, it is used to model dopaminergic blockade and to probe downstream effects on pathways associated with Gi or Go coupled receptor signaling, including modulation of cyclic AMP dependent signaling dynamics, neuronal excitability, and network level responses relevant to movement and affect related phenotypes, while in biomedical research and discovery workflows it is commonly applied in receptor binding assays, cell based functional assays, and exploratory animal model paradigms focused on dyskinesia related phenotypes, neurobehavioral endpoints, and central dopamine system perturbation, with concentrations or doses used in experiments typically determined by assay format, species, exposure window, and specific research objectives.