TED-347
Catalog No.
BA9123
TED-347 is a potent, irreversible and covalent protein-protein interaction denaturing inhibitor.
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TED-347 is a potent, irreversible and covalent mutational inhibitor of protein-protein interactions with a value of 5.9 μM for TEAD4?Yap1 protein-protein interactions.TED-347 specifically covalently binds to Cys-367 within the central pocket of TEAD4 with a value of 10.3 μM.TED-347 blocks TEAD transcriptional activity and has antitumor activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 313.70 |
| Cas No. | 2378626-29-8 |
| Formula | C15H11ClF3NO |
| Solubility | ≥52.3 mg/mL in DMSO; ≥24.85 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 2-chloro-1-(2-((3-(trifluoromethyl)phenyl)amino)phenyl)ethan-1-one |
| SDF | Download SDF |
| Canonical SMILES | O=C(CCl)C1=CC=CC=C1NC2=CC=CC(C(F)(F)F)=C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
