Talniflumate
Catalog No.
B7086
Calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker
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Talniflumate (CAS No.: 66898-62-2) is an anti-inflammatory drug and a prodrug of niflumic acid, mainly used to study mucin regulation in diseases such as cystic fibrosis, chronic obstructive pulmonary disease (COPD), and asthma. In addition, Talniflumate has been studied as an inhibitor of human calcium-activated chloride channels, showing anti-inflammatory and analgesic activity. In in vitro studies, its activity is typically in the low micromolar range. The dose or concentration used in experiments usually depends on the experimental design and research objectives.
| Physical Appearance | White solid |
| Storage | Store at -20°C |
| M.Wt | 414.34 |
| Cas No. | 66898-62-2 |
| Formula | C21H13F3N2O4 |
| Solubility | <10.36mg/ml in DMSO |
| Chemical Name | (S)-3-oxo-1,3-dihydroisobenzofuran-1-yl 2-((3-(trifluoromethyl)phenyl)amino)nicotinate |
| SDF | Download SDF |
| Canonical SMILES | O=C(c1cccnc1Nc1cccc(C(F)(F)F)c1)O[C@@H](c1c2cccc1)OC2=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
