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Taletrectinib adipate

Catalog No.
BA9008
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Taletrectinib (DS-6051b) is a potent and orally active next-generation selective inhibitor.
Grouped product items
Size Price Stock Qty
1mL(10 mM in DMSO)
$212.00
In stock
1mg
$79.00
In stock
5mg
$175.00
In stock
10mg
$279.00
In stock
25mg
$502.00
Ships within 10-15 days
50mg
$801.00
Ships within 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Taletrectinib (DS-6051b) is a potent, orally active, next-generation selective inhibitor.Taletrectinib showed strong inhibition of recombinant ROS1, NTRK1, NTRK2, and NTRK3 at 0.207, 0.622, 2.28, and 0.98 nM, respectively.Taletrectinib also inhibited ROS1G2032R and other anti-Crizotinib ROS1 mutants.

Chemical Properties

Physical AppearanceA solid
StorageTightly sealed and desiccated at 4°C
M.Wt551.61
Cas No.1505515-69-4
FormulaC29H34FN5O5
SynonymsDS-6051b;AB-106;IBI-344
Solubility≥17.2 mg/mL in DMSO with ultrasonic; ≥2.63 mg/mL in EtOH with gentle warming and ultrasonic; insoluble in H2O
Chemical Name3-(4-((R)-2-aminopropoxy)phenyl)-N-((R)-1-(3-fluorophenyl)ethyl)imidazo[1,2-b]pyridazin-6-amine adipate
Canonical SMILESO=C(O)CCCCC(O)=O.C[C@@H](NC1=NN2C(C=C1)=NC=C2C3=CC=C(OC[C@H](N)C)C=C3)C4=CC=CC(F)=C4
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure
Taletrectinib adipate

 

User Guide

  • General User Guide for APExBIO Small Molecule Compounds