SRI-37240
Catalog No.
BA6623
SRI-37240 is a potent early termination codon inhibitor.
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SRI-37240 is a potent early termination codon inhibitor. nonsense mutations suppressed by SRI-37240. In HEK293T cells, SRI-37240 altered cellular translation termination in PTCs. When used in combination with G418, SRI-37240 also restores the function of primary bronchial epithelial cells.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 385.46 |
Cas No. | 883956-47-6 |
Formula | C24H23N3O2 |
Solubility | ≥10.06 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O |
Chemical Name | 3-cyclohexyl-10-methyl-2-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione |
SDF | Download SDF |
Canonical SMILES | CN1C2=C(C(N(C3CCCCC3)C(C4=CC=CC=C4)=N2)=O)C(C5=C1C=CC=C5)=O |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
