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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A1670 Enzastaurin (LY317615)
2 Citation

Target: PKC

Summary: PKC beta inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
A5096 PF-04217903

Target: c-MET

Summary: C-Met inhibitor,selective and ATP-competitive

insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL
A2782 Amonafide

Summary: DNA intercalator,Topo II inhibitor

insoluble in EtOH; insoluble in H2O; ≥14.17 mg/mL
A1659 Dutasteride

Target: 5-alpha Reductases

Summary: 5-alpha-reductase inhibitor

≥26.43 mg/mL
A2451 Epirubicin HCl

Target: Topoisomerases

Summary: Antibiotic antitumor agent

≥29.00 mg/mL
A1196 SGX-523
1 Citation

Target: MET

Summary: MET inibitor, highly selective, ATP-competitive

≥17.95 mg/mL
A5112 XL147

Target: PI3K

Summary: PI3K inhibitor,selective and reversible

≥22.45 mg/mL
A2681 TGX-221

Target: PI3K

Summary: PI3Kβ inhibitor,potent,selective and ATP competitive

insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
A2949 Linifanib (ABT-869)

Target: VEGFR|PDGFR

Summary: VEGFR/PDGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
A1185 BMS-754807

Target: Insulin and Insulin-like Receptors

Summary: IGF-1R/InsR inhibitor,potent and selective

≥23.05 mg/mL