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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B7800 BAW2881 (NVP-BAW2881)

Summary: VEGFR inhibitor

≥42.4 mg/mL
B7801 CPI-637

Summary: CBP/EP300 bromodomain inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.3 mg/mL
B7802 APTSTAT3-9R

Summary: STAT3 inhibitor

Soluble in DMSO
B7803 MK-4101

Summary: Hedgehog (Hh) signaling pathway inhibitor

Soluble in DMSO
B7804 AG-221 (Enasidenib)

Summary: mutant isocitrate dehydrogenase 2 (IDH2) inhibitor

≥47.3 mg/mL
B7805 AG-120

Summary: mutant IDH1 inhibitor

≥58.3 mg/mL
B7806 HLCL-61

Summary: PRMT5 inhibitor

≥20.4 mg/mL
B7808 NT157
1 Citation

Summary: IRS-1/2 inhibitor, inhibits IGF-1R and STAT3 signaling pathway
B7809 Ponesimod

Summary: sphingosine-1-phosphate receptor 1 (S1P1) modulator

≥50.6 mg/mL
B7810 RK-33

Target: DDX3

Summary: DDX3 (a RNA helicase) inhibitor

≥21.4 mg/mL