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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B7811 CPI-455 HCl

Summary: KDM5 inhibitor

≥31.5 mg/mL
B7812 Selonsertib (GS-4997)

Summary: apoptosis signal-regulating kinase 1 (ASK1) inhibitor

≥44.5 mg/mL
B7813 Olmutinib (HM61713, BI 1482694)

Summary: EGFR mutant-specific inhibitor
B7814 ATI-2341 TFA

Summary: CXCR4 allosteric agonist

Soluble in DMSO
B7815 NSC228155

Summary: EGFR activator

≥29 mg/mL
B7816 ITSA-1 (ITSA1)

Summary: HDAC activator via Trichostatin A (TSA) suppression

insoluble in H2O; insoluble in EtOH; ≥89 mg/mL
B7818 ONO-7300243

Target: LPA

Summary: LPA1 antagonist

≥46.1 mg/mL
B7819 CPI-1205

Summary: EZH2 inhibitor

Soluble in DMSO
B7820 APS-2-79

Summary: KSR-dependent MAPK modulator

Soluble in DMSO
B7821 AZD9496

Summary: estrogen receptor inhibitor, orally active

Soluble in DMSO