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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B6190 NSC348884

Summary: nucleophosmin inhibitor

≥63.7 mg/mL
B6191 PD-1/PD-L1 Inhibitor 3

Summary: PD-1/PD-L1 interaction inhibitor

Soluble in DMSO
B6192 ON123300

Summary: multi-targeted kinase inhibitor,inhibits CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn

≥21.5 mg/mL
B6193 AMG 337

Summary: MET inhibitor

≥46.3 mg/mL
B6194 GSK481

Summary: RIP1(Receptor Interacting Protein Kinase 1) inhibitor

Soluble in DMSO
B6195 Verubecestat (MK-8931)

Summary: Orally active β-secretase 1 (BACE1) inhibitor; reduces β-amyloid production

insoluble in H2O; insoluble in EtOH; ≥40.9 mg/mL
B6196 BI-7273

Summary: BRD9 bromodomain inhibitor

≥35.3 mg/mL
B6197 PF-CBP1 hydrochloride

Summary: CBP/p300 bromodomain inhibitor

≥52.5 mg/mL
B6198 ReACp53

Summary: inhibit p53 amyloid formation

Soluble in DMSO
B6199 BFH772

Summary: VEGFR2 inhibitor

≥53.4 mg/mL