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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B4887 Remodelin hydrobromide

Target: NAT10

Summary: NAT10 inhibitor

≥36.3 mg/mL
B4888 Obeticholic Acid
2 Citation

Target: Farnesoid X receptors (FXRs)

Summary: FXR agonist with anticholeretic activity

≥21.5 mg/mL
B4889 Verdinexor (KPT-335)

Summary: XPO1/CRM1 inhibitor

≥44.2 mg/mL
B4799 Telaglenastat
1 Citation

Target: Glutaminases

Summary: Orally active glutaminase inhibitor

≥28.6 mg/mL
B4800 Defactinib

Target: FAK

Summary: FAK phosphorylation inhibitor

insoluble in EtOH; insoluble in H2O; ≥160.2 mg/mL
B4803 PEAQX

Summary: NMDA antagonist

Soluble in DMSO
B4807 Firocoxib

Summary: COX2 inhibitor

Soluble in DMSO
B4808 RG7090

Summary: negative modulator of mGluR5

Soluble in DMSO
B4809 K-115

Summary: Selective Rho kinase inhibitor

insoluble in EtOH; ≥123.2 mg/mL
B4811 Afuresertib

Summary: pan-AKT inhibitor

≥2.71 mg/mL