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Savolitinib

Catalog No.
BA8873
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Savolitinib (AZD-6094) is a highly potent selective, oral bioavailability inhibitor with ICs of 5nM and 3nM for c-Met and p-Met, respectively.
Grouped product items
Size Price Stock Qty
1mL(10 mM in DMSO)
$170.00
In stock
2mg
$72.00
In stock
5mg
$144.00
In stock
10mg
$198.00
In stock
25mg
$324.00
Ships within 10-15 days
50mg
$468.00
Ships within 10-15 days
100mg
$666.00
Ships within 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Savolitinib (AZD-6094) is a potent and selective, oral bioavailability inhibitor with ICs of 5 nM and 3 nM for c-Met and p-Met, respectively.Savolitinib (AZD-6094) selectively binds and inhibits c-Met activation in an ATP-competitive manner, disrupting the c-Met signaling pathway. It has anti-tumor activity.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt345.36
Cas No.1313725-88-0
FormulaC17H15N9
SynonymsVolitinib;HMPL-504;AZD-6094
Solubility≥10.5 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O
Chemical Name(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
Canonical SMILES[C@@H](C)(N1C=2C(N=N1)=NC=C(N2)C3=CN(C)N=C3)C4=CN5C(C=C4)=NC=C5
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure
Savolitinib

 

User Guide

  • General User Guide for APExBIO Small Molecule Compounds