S116836
Catalog No.
BA3198
S116836 is a potent, orally active tyrosine kinase inhibitor (TKI) that blocks both wild-type and T315I.
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S116836 is a potent, orally active tyrosine kinase inhibitor (TKI) that blocks wild-type and T315I.S116836 blocks BaF3/WT and BaF3/T315I cells in the G0/G1 phase of the cell cycle, induces apoptosis, increases ROS production, and decreases GSH production.S116836 also inhibits SRC, LYN, HCK, LCK, and BLK, as well as receptor tyrosine kinases such as FLT3, TIE2, KIT, and PDGFR-β. has antitumor activity.
| Physical Appearance | A solid |
| Storage | 4°C |
| M.Wt | 502.49 |
| Cas No. | 1257628-57-1 |
| Formula | C27H21F3N6O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |