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Prostaglandin F2α ethanolamide

Catalog No.
A9077
Prostaglandin F2α ethanolamide is an ethanolamide-class G protein-coupled receptor (GPCR). It also acts as a luteolytic hormone in sheep and may serve as a nociceptive mediator in the spinal cord.
Grouped product items
SizePriceStock Qty
1mg
$160.00
Ship with 10-15 days
5mg
$700.00
Ship with 10-15 days
10mg
$1,300.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Description

Prostaglandin F2α ethanolamide is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues.1 AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs.It has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.

Chemical Properties

StorageStore at -20°C
M.Wt397.56
Cas No.353787-70-9
FormulaC22H39NO5
SynonymsProstamide F2α,PGF2α-EA
SolubilitySoluble in DMSO
Chemical Name(Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)-N-(2-hydroxyethyl)hept-5-enamide
SDFDownload SDF
Canonical SMILESO[C@@H]1[C@H](C/C=C\CCCC(NCCO)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

Prostaglandin F2α ethanolamide