Picrotoxin
Catalog No.
B5054
GABAA receptor antagonist
Featured Products
B5054 is a small molecule utilized in biomedical research as a pharmacological probe. Although its precise biological target has not yet been publicly disclosed, compounds similar to B5054 typically function by modulating intracellular signaling pathways or enzymatic activities that influence cellular proliferation, differentiation, or apoptosis. B5054 is primarily employed by researchers to investigate molecular mechanisms underlying disease pathogenesis, evaluate cellular responses, and explore potential therapeutic targets in preclinical experimental settings.
- 1. Jing Wang, Yue Gao, et al. "Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1−/− mice." iScience. 2023 Jul 25;26(8):107476. PMID: 37599823
- 2. Yun Zhang, Yixin Zhang, et al. "Inhibition of glutamatergic trigeminal nucleus caudalis-vestibular nucleus projection neurons attenuates vestibular dysfunction in the chronic-NTG model of migraine." J Headache Pain. 2023 Jun 30;24(1):77. PMID: 37386456
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 602.59 |
| Cas No. | 124-87-8 |
| Formula | C30H34O13 |
| Solubility | ≥24.55 mg/mL in DMSO; ≥2.3 mg/mL in H2O with gentle warming and ultrasonic; ≥45.2 mg/mL in EtOH |
| SDF | Download SDF |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
