PF-06821497
Catalog No.
BA4686
PF-06821497 is a potent, selective, and orally effective inhibitor.
Featured Products
PF-06821497 is a potent, selective, and orally effective inhibitor of Y641N with a value of <0.1 nM.Good antitumor activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 467.34 |
| Cas No. | 1844849-10-0 |
| Formula | C22H24Cl2N2O5 |
| Solubility | ≥25.35 mg/mL in DMSO; ≥10.04 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (R)-5,8-dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one |
| SDF | Download SDF |
| Canonical SMILES | O=C1C(CN(C2=O)CCC(C2=C3Cl)=C(Cl)C=C3[C@H](OC)C4COC4)=C(OC)C=C(C)N1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








