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Pertussis Toxin

Catalog No.
B7273
causes whooping cough
Grouped product items
SizePriceStock Qty
50ug
$965.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Email: [email protected]

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Background

Pertussis toxin (CAS: 70323-44-3) is an AB5-type protein exotoxin produced by Bordetella pertussis, the bacterium responsible for whooping cough. Mechanistically, pertussis toxin modulates host immune responses primarily via a cAMP-dependent pathway, as demonstrated by its actions on human monocyte-derived dendritic cells, influencing their maturation and cytokine production. In animal models, treatment reduces norepinephrine-induced contractions in rat mesenteric resistance arteries without notable effects on mouse tracheal contractility. Pertussis toxin serves as a research tool in immunological studies and is central to acellular pertussis vaccines designed to limit disease transmission and severity across susceptible populations.

Product Citation

Chemical Properties

Physical AppearanceEach vial, when reconstituted to 500 μL with water, contains 50 μg of pertussis toxin in 0.01 M sodium phosphate, 0.05 M sodium chloride, pH 7.0
StorageDesiccate at 4°C
Cas No.70323-44-3
SolubilitySoluble in H2O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Related Biological Data

Pertussis Toxin