Pemafibrate
Catalog No.
BA4427
An inhibitor.
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Pemafibrate is a highly selective peroxisome proliferator-activated receptor α (PPARα) agonist that can activate the transcriptional activity of PPARα with high affinity. Experimental studies have confirmed that the half-maximal effective concentration (EC50) of this compound is approximately 1 nM, indicating strong receptor agonist activity. As an important nuclear receptor in metabolic regulation, PPARα is involved in biological pathways such as lipid metabolism and inflammatory responses. Pemafibrate is commonly used in biomedical research to investigate mechanisms of lipid metabolism and to evaluate metabolism pathway-related diseases such as hyperlipidemia, atherosclerosis, and other metabolism-related pathological changes.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 490.55 |
| Cas No. | 848259-27-8 |
| Formula | C28H30N2O6 |
| Synonyms | (R)-K-13675 |
| Solubility | ≥54.2 mg/mL in DMSO; ≥10.36 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid |
| SDF | Download SDF |
| Canonical SMILES | N(CC1=CC(O[C@@H](C(O)=O)CC)=CC=C1)(CCCOC2=CC=C(OC)C=C2)C3=NC=4C(O3)=CC=CC4 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |