Pantoprazole Sodium
Catalog No.
C8706
Benzimidazole proton pump inhibitor (PPI)
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Pantoprazole is a benzimidazole proton pump inhibitor (PPI) and an irreversible inhibitor of H⁺/K⁺‑ATPase.[PMC3079481] After oral administration, it is protonated in the acidic environment of the secretory canaliculi of parietal cells and converted to an active sulfenamide, which forms covalent bonds with cysteine residues of the pump protein, inhibiting basal and stimulated gastric acid secretion. Acid suppression persists until new pumps are synthesized and is associated with standard treatment of acid-related diseases (GERD, peptic ulcer, etc.). Long-term use is associated with hypergastrinemia, ECL cell hyperplasia, and increased risks of fractures and infections.
| Storage | 4℃, sealed storage, away from moisture and light |
| M.Wt | 406.36 |
| Cas No. | 138786-67-1 |
| Formula | C16H15F2N3O4S•Na |
| Synonyms | BY1023 sodium; SKF96022 sodium |
| Chemical Name | 5-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, sodium salt |
| SDF | Download SDF |
| Canonical SMILES | [Na].O=S(C1=NC=2C=C(OC(F)F)C=CC2N1)CC3=NC=CC(OC)=C3OC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |