Oxoadipic acid
2-Oxoadipic acid (CAS No.3184-35-8 ) is an intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine.[1][2]Urinary excretion of 2-oxoadipic acid is increased in patients with α-ketoadipic aciduria, a rare inborn error of metabolism affecting the conversion of 2-oxoadipic acid to glutaryl-coenzyme A (glutaryl-CoA).
Reference:
1. Xia ZW, Inoue Y, Ohse M, Shinka T, Kuhara T. A study on alpha-ketoadipic aciduria by gas chromatographic-mass spectrometry. World J Gastroenterol. 2000 Oct;6(5):766-769. doi: 10.3748/wjg.v6.i5.766. PMID: 11819692; PMCID: PMC4688861.
2. Gray RG, O'Neill EM, Pollitt RJ. Alpha-aminoadipic aciduria: chemical and enzymatic studies. J Inherit Metab Dis. 1980;2(4):89-92. doi: 10.1007/BF01805664. PMID: 6796766.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 160.13 |
| Cas No. | 3184-35-8 |
| Formula | C6H8O5 |
| Synonyms | 2-Oxoadipic Acid; α-Ketoadipate; 2-Ketoadipic Acid; α-Ketoadipic Acid; α-Oxoadipic Acid |
| Solubility | Soluble in DMSO |
| Chemical Name | 2-oxohexanedioic acid |
| SDF | Download SDF |
| Canonical SMILES | OC(C(CCCC(O)=O)=O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
