Orelabrutinib
Catalog No.
BA8819
Orelabrutinib (ICP-022) is a potent, orally active, irreversible Bruton tyrosine kinase inhibitor with potential antitumor activity.
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Orelabrutinib (ICP-022) is a potent, orally active, irreversible Bruton's tyrosine kinase inhibitor with potential antitumor activity.Orelabrutinib prevents the activation of the B-cell antigen receptor (BCR) signaling pathway and mediates the activation of the downstream survival pathway, inhibiting the growth of overexpressing malignant B cells.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 427.50 |
| Cas No. | 1655504-04-3 |
| Formula | C26H25N3O3 |
| Synonyms | ICP-022 |
| Chemical Name | 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide |
| Canonical SMILES | O=C(C1=CC=C(C2CCN(C(C=C)=O)CC2)N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure







