NRX-0492
Catalog No.
BA8837
NRX-0492 is an orally effective degradant.
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NRX-0492 is an orally effective degradative agent.NRX-0492 catalyzes ubiquitination and proteasomal degradation (DC ≤ 0.2 nM, DC ≤ 0.5 nM).NRX-0492 inhibits B-cell receptor (BCR)-mediated signaling, transcriptional programs, and chemokine secretion.NRX-0492 is capable of linking non-covalent binding domains to.Cereblon is an E3 an articulating protein of the ubiquitin ligase complex.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 817.94 |
Cas No. | 2416130-57-7 |
Formula | C43H51N11O6 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |