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NPE-caged-proton

Catalog No.
B7416
Generates rapid acidifications down to pH 2
Grouped product items
SizePriceStock Qty
10mg
$530.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

NPE-caged-proton (CAS 1186195-63-0) is a small molecule reagent designed to achieve precise, photo-induced acidification in biological environments. Upon photoactivation, this compound rapidly releases protons, lowering the local pH to as low as 2.0. Studies demonstrate that controlled acidification between pH 4.0 and 5.5 activates the fusion protein GP64, promoting binding of enveloped viruses to acidic phospholipid-containing liposomes and subsequently triggering membrane fusion events. In viral entry and membrane interaction assays, NPE-caged-proton facilitates exploration of molecular interactions under defined acidic conditions, making it a valuable research reagent for investigating virus-host interactions and membrane fusion mechanisms.

Chemical Properties

Physical AppearanceOff White solid
StorageStore at -20°C
M.Wt269.21
Cas No.1186195-63-0
FormulaC8H8NNaO6S
Solubility<26.92mg/ml in H2O; <26.92mg/ml in DMSO
Chemical Namesodium (R)-1-(2-nitrophenyl)ethyl sulfate
SDFDownload SDF
Canonical SMILES[O-][N+](C1=CC=CC=C1[C@@H](C)OS([O-])(=O)=O)=O.[Na+]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

NPE-caged-proton