Nonadecanoic Acid

Nonadecanoic Acid (CAS No.: 646-30-0) is a long-chain saturated fatty acid widely distributed in natural sources including fungi, plants, marine organisms, and certain bacterial species, and is also present in fats and vegetable oils, making it a relevant lipid molecule for biochemical and metabolic studies. Functionally, it plays a role in modulating lipid metabolism by influencing cellular membrane lipid composition, thereby affecting membrane fluidity and associated signaling pathways that regulate cellular homeostasis. In biochemical assays, nonadecanoic acid has been reported to inhibit fibrinolysis and plasmin activity, and to modulate immune-related signaling such as suppression of IL-12 production, indicating potential involvement in inflammatory and immune regulatory pathways. Additionally, it has demonstrated antiproliferative activity in cancer cell models, including inhibition of HL-60 leukemia cell growth at low micromolar concentrations, supporting its relevance in oncology-related research. As a metabolically stable fatty acid, it is frequently employed as a reference standard or internal control in lipidomics and metabolomics workflows to quantify fatty acid profiles and investigate lipid metabolic disorders. In experimental settings, it is utilized in cell-based assays and biochemical studies to probe fatty acid-mediated signaling and metabolic alterations, with concentrations or dosing regimens adjusted according to specific study designs and objectives in drug discovery and disease mechanism research.