NCT-58
Catalog No.
BA3053
NCT-58 is a potent inhibitor of the C-terminus.
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NCT-58 is a potent inhibitor of the C-terminus.NCT-58 does not induce a heat shock response (HSR) because it targets the C-terminal region and triggers antitumor activity by simultaneously down-regulating members of the HER family as well as by inhibiting phosphorylation.NCT-58 kills trastuzumab-resistant (Trastuzumab-resistant) breast cancer stem cell-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells. In a trastuzumab-resistant xenograft model, NCT-58 inhibited growth and angiogenesis.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 466.57 |
| Cas No. | 2411429-33-7 |
| Formula | C27H34N2O5 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |