NAZ2329
Catalog No.
BA8084
NAZ2329 is the first cell-permeable inhibitor of the R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs)
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NAZ2329 is the first cell-permeable inhibitor of the R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), and it metastably and preferentially inhibits (hPTPRZ1=7.5μM) and (hPTPRG=4.8μM) relative to other PTPs.NAZ2329 binds to the D1 structural domain, and is more effective in inhibiting the PTPRZ1-D1 fragment relative to the entire (D1+D2) fragment at a value of 1.1μM. effectively inhibits the PTPRZ1-D1 fragment with a value of 1.1 μM.NAZ2329 effectively inhibits tumor growth and suppresses stem cell-like properties in glioblastoma cells.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 501.56 |
| Cas No. | 2809469-05-2 |
| Formula | C21H18F3NO4S3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |