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NADP sodium salt

Catalog No.
B8375
A coenzyme reagent widely used in research on cellular metabolism and redox homeostasis.
Grouped product items
SizePriceStock Qty
100mg
$50.00
In stock
500mg
$160.00
In stock
1g
$265.00
In stock
5g
$386.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

NADP sodium salt (CAS No.: 1184-16-3) is a biologically ubiquitous coenzyme that functions as a central redox carrier in cellular metabolism, cycling between its oxidized (NADP?) and reduced (NADPH) states to mediate electron transfer reactions. Widely distributed across prokaryotic and eukaryotic systems, it plays a critical role in maintaining intracellular redox homeostasis and supports anabolic pathways by serving as a primary electron donor for biosynthetic processes, including lipid, nucleotide, and amino acid synthesis. NADPH-dependent systems are also integral to antioxidant defense mechanisms and the regulation of oxidative stress, as well as to signaling pathways associated with inflammation and metabolic adaptation. Through its involvement in enzymatic reactions such as those catalyzed by oxidoreductases and dehydrogenases, NADP/NADPH participates in key pathways including the pentose phosphate pathway and cellular detoxification processes. Although specific potency metrics such as IC50 or EC50 are not typically defined for this endogenous cofactor, its functional activity is generally evaluated within physiological or experimentally controlled concentration ranges spanning nanomolar to micromolar levels depending on the system. NADP sodium salt is commonly utilized in biochemical assays, cell-based metabolic studies, and enzymatic activity analyses, as well as in investigations of redox biology and disease-related metabolic dysregulation, with experimental concentrations tailored to the requirements of specific models and study designs.

Chemical Properties

Physical AppearanceSolid
Storage -20°C
M.Wt765.39
Cas No.1184-16-3
FormulaC21H27N7NaO17P3
SynonymsSodium NADP
Solubilityinsoluble in EtOH; insoluble in DMSO; ≥61.7 mg/mL in H2O
Canonical SMILESNC1=C2N=CN([C@H]3[C@H](OP(O)(O)=O)[C@H](O)[C@@H](COP(OP([O-])(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H]([N+]5=CC=CC(C(N)=O)=C5)O4)=O)([O-])=O)O3)C2=NC=N1.[Na+]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

User Guide