N4-Methyl-dCTP
N4-Methyl-dCTP is a cytosine-derived modified deoxynucleoside triphosphate capable of being enzymatically incorporated into DNA strands, thereby introducing cytosine methylation modifications at specific genomic sites. DNA methylation at the N4 position of cytosine is observed naturally across both prokaryotic and eukaryotic organisms and influences processes such as epigenetic gene expression regulation, DNA replication, and DNA damage repair. Researchers use N4-Methyl-dCTP to incorporate defined methylation modifications, enabling investigation into methylation-specific DNA-binding protein interactions, DNA methylation patterning analyses, and functional studies of epigenetic modification pathways.
Physical Appearance | Solution |
Storage | Store at -20°C or below |
M.Wt | 481.1 (free acid) |
Formula | C10H18N3O13P3 (free acid) |
Synonyms | N4-Methyl-2'-deoxycytidine-5'-Triphosphate |
Chemical Name | lithium (3-hydroxy-5-(4-(methylamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
SDF | Download SDF |
Canonical SMILES | OC1C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)OC(N2C=CC(NC)=NC2=O)C1.[Li+].[Li+].[Li+].[Li+] |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = ≥90% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
