N,N'-Dinitrosopiperazine

N,N'-Dinitrosopiperazine (CAS No.: 140-79-4) is a known carcinogenic substance, mainly closely associated with the occurrence and metastasis of nasopharyngeal carcinoma. Its carcinogenic mechanism involves multiple signaling pathways, particularly acting through regulation of phosphorylation at the Ser568 site of the LYRIC protein. N,N'-Dinitrosopiperazine is commonly used to induce esophageal cancer models to study tumor initiation and progression and potential therapeutic strategies. The dose or concentration used in experiments usually depends on the experimental design and research objectives. In addition, this compound is also used to study its effects on protein phosphorylation, further elucidating its mechanistic role in tumor progression.