N-Butyl-N-(4-hydroxybutyl)nitrosamine
Catalog No.
C8738
A compound commonly used to induce bladder cancer in animal models.
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N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN, CAS 3817-11-6) is a chemical compound commonly used in biomedical research, mainly to induce bladder cancer in animal models. Its mechanism involves mutagenesis of urothelial cells, causing high levels of mutations in bladder epithelial cells and thereby promoting tumor formation. In animal models, N-Butyl-N-(4-hydroxybutyl)nitrosamine is usually administered through drinking water or gavage to induce bladder cancer. In addition, the compound is also used to study the pathogenesis of bladder cancer, screen potential therapeutic drugs, and evaluate the effectiveness of preventive measures.
| Storage | Store at -20°C |
| M.Wt | 174.24 |
| Cas No. | 3817-11-6 |
| Formula | C8H18N2O2 |
| Synonyms | BBN; Butylbutanolnitrosamine; 4-Hydroxybutylbutylnitrosamine |
| Solubility | ≥31 mg/mL in DMSO; ≥28 mg/mL in EtOH; ≥23.9 mg/mL in H2O |
| Chemical Name | N-butyl-N-(4-hydroxybutyl)nitrous amide |
| Canonical SMILES | O=NN(CCCC)CCCCO |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
