Morantel tartrate

Morantel tartrate (CAS No.: 26155-31-7) is a synthetic tetrahydropyrimidine class anthelmintic and veterinary research compound that is widely used as a pharmacological tool in parasitology and neuropharmacology focused on nematode biology, where it is primarily categorized as an antiparasitic probe and receptor modulator for experimental systems rather than any human use context; mechanistically, available evidence indicates activity at nicotinic acetylcholine receptor signaling, including positive allosteric modulation of neuronal nAChR subtypes in model systems and functional disruption of cholinergic neuromuscular transmission in susceptible helminths, thereby supporting studies of parasite motility, feeding behavior, and survival under controlled laboratory conditions; consistent with this mode of action, it is commonly applied in gastrointestinal nematode infection models in livestock associated research, including investigations of fecal egg count reduction and parasite burden dynamics, and it is also used in comparative screening workflows that examine cholinergic ligand sensitivity, resistance phenotypes, and structure activity relationships across antiparasitic chemotypes; publicly summarized records do not consistently report standardized potency metrics for this exact salt form across unified assay platforms, so in vitro effects are generally interpreted qualitatively or in broad concentration windows that can extend from micromolar to higher testing ranges depending on receptor system, parasite species, and assay endpoint, while experimental concentrations or doses are selected according to specific study design, formulation strategy, and research objectives in cell based assays, ex vivo preparations, and animal infection studies.