ML364
Catalog No.
BA3879
ML364 is a ubiquitin protein-specific peptidase inhibitor (=1.1 μM) with antiproliferative activity that binds directly to USP2 (=5.2 μM), inducing increased degradation of the cell cycle protein D1 and leading to cell cycle arrest.
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ML364 is a ubiquitin protein-specific peptidase inhibitor (=1.1 μM) with antiproliferative activity that directly binds to USP2 (=5.2 μM), inducing increased degradation of the cell cycle protein D1 and leading to cell cycle arrest.ML364 increases mitochondrial reactive oxygen species (ROS) levels and decreases intracellular ATP content.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 517.54 |
| Cas No. | 1991986-30-1 |
| Formula | C24H18F3N3O3S2 |
| Solubility | ≥24.3 mg/mL in DMSO with ultrasonic; ≥9.72 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 2-((4-methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide |
| Canonical SMILES | O=C(NC1=NC(C2=CC=CC=C2)=CS1)C3=CC=C(C(F)(F)F)C=C3NS(=O)(C4=CC=C(C)C=C4)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
