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MIP-3beta, murine recombinant protein

Catalog No.
P1049
MIP-3β, chemokine, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
20ug
$264.00
Ship with 5-10 days
100ug
$824.00
Ship with 5-10 days
1mg
$5,475.00
Ship with 5-10 days

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Email: [email protected]

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Background

Macrophage inflammatory protein-3 β (MIP-3β) is a CC chemokine produced in the thymus, lymph nodes and activated bone marrow stromal cells. MIP-3β signals through the chemokine receptor CCR-7/EBI-1/BLR-2. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. The expression of MIP-3β is down-regulated by the anti-inflammatory cytokine IL-10. CCL19 and CCL21 control survival, apoptosis, migratory speed, and maturation of dendritic cells, rate of endocytosis and the cytoarchitecture.

The murine MIP-3β cDNA encodes a 108 aa protein contains a 25 aa signal sequence. Human MIP-3β is active on murine cells. Recombinant murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues.

Biological Activity

Determined by its ability to chemoattract human mature dendritic cells using a concentration of 10-100 ng/ml.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.1 ng/μg/span>
 

Description

Gene ID: 24047 Accession #: O70460
Alternate Names:Murine MIP-3beta, m-MIP-3beta, rm-MIP-3beta, MIP-3beta, MIP3beta, MIP3 beta,recombinant murine MIP-3beta, recombinant MIP-3beta, MIP.
Source: Escherichia Coli. M.Wt: 9.2 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.