Mercaptopurine (6-MP)
Catalog No.
A2355
Purine synthesis inhibitor
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Mercaptopurine (6-MP, CAS: 50-44-2) is a purine analog that disrupts de novo purine biosynthesis by incorporating into nucleic acids, thereby inhibiting DNA and RNA synthesis. This mode of action results in cytotoxic and immunosuppressive effects, making the compound a valuable tool in studies of cell proliferation, immune response modulation, and leukemia research. 6-MP serves as the active metabolite of azathioprine, and it is also used to investigate the interaction between purine metabolism inhibitors and anticoagulant agents such as warfarin.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 152.18 |
| Cas No. | 50-44-2 |
| Formula | C5H4N4S |
| Solubility | insoluble in EtOH; insoluble in H2O; ≥7.61 mg/mL in DMSO |
| Chemical Name | 3,7-dihydropurine-6-thione |
| SDF | Download SDF |
| Canonical SMILES | S=C1N=CNc2c1[nH]cn2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
