Melatonin
Catalog No.
A2842
Melatonin receptors agonist
Featured Products
Melatonin (CAS 73-31-4) is a naturally occurring hormone functioning primarily as an agonist at the G protein-coupled melatonin receptors MT? and MT?. Through receptor activation, melatonin regulates circadian rhythmicity and contributes significantly to sleep-wake cycle maintenance. Additionally, melatonin demonstrates immunomodulatory capabilities and possesses robust antioxidant properties in vivo, combating oxidative stress. Due to these characteristics, it is frequently investigated in research related to sleep disorders, circadian biology, immune function, and oxidative stress signaling pathways.
- 1. Xiao Sun, Ping Sun, et al. "Melatonin alleviates doxorubicin-induced mitochondrial oxidative damage and ferroptosis in cardiomyocytes by regulating YAP expression." Toxicol Appl Pharmacol. 2022 Feb 15;437:115902. PMID: 35093381
- 2. Yina Liao, Yao Gao, et al. "Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling." J Cell Mol Med. 2020 Sep 15. PMID:32935463
| Storage | Store at -20°C |
| M.Wt | 232.28 |
| Cas No. | 73-31-4 |
| Formula | C13H16N2O2 |
| Solubility | ≥23.2 mg/mL in DMSO; insoluble in H2O; ≥79.9 mg/mL in EtOH |
| Chemical Name | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide |
| SDF | Download SDF |
| Canonical SMILES | CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
Related Biological Data
