Toggle Nav
Close
  • Menu
  • Setting

MBX-2982

Catalog No.
A3587
GPR119 agonist,selective and orally-available
Grouped product items
SizePriceStock Qty
5mg
$176.00
Ship with 10-15 days
10mg
$298.00
Ship with 10-15 days
50mg
$1,018.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health.

Chemical Properties

StorageStore at -20°C
M.Wt448.54
Cas No.1037792-44-1
FormulaC22H24N8OS
SynonymsMBX 2982;MBX2982
SolubilitySoluble in DMSO
Chemical Name2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole
SDFDownload SDF
Canonical SMILESCCC1=CN=C(N=C1)N2CCC(CC2)C3=NC(=CS3)COC4=CC=C(C=C4)N5C=NN=N5
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

MBX-2982