Lurasidone
Catalog No.
BA4992
Lurasidone (SM-13496) is the antagonist.
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Lurasidone (CAS No.: 367514-87-2) is a novel atypical antipsychotic mainly used for the treatment of schizophrenia and depressive episodes associated with bipolar I disorder. Its mechanism of action involves antagonism at dopamine D2 receptors, serotonin (5-HT)2A receptors, and 5-HT7 receptors, as well as partial agonism at 5-HT1A receptors. In vitro studies show that Lurasidone has high affinity for the above receptors, with activity in the nanomolar to low micromolar range. This compound is commonly used in cell-based and animal models to evaluate its modulatory effects on neurotransmitter systems and antipsychotic efficacy. The doses or concentrations used in experiments typically depend on the experimental design and research objectives.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 492.68 |
| Cas No. | 367514-87-2 |
| Formula | C28H36N4O2S |
| Synonyms | SM-13496 |
| Solubility | ≥6.85 mg/mL in DMSO with ultrasonic; ≥5.31 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione |
| Canonical SMILES | O=C1[C@]2([C@]([C@]3(C[C@@]2(CC3)[H])[H])(C(=O)N1C[C@H]4[C@H](CN5CCN(CC5)C=6C=7C(SN6)=CC=CC7)CCCC4)[H])[H] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |