LTGO-33
Catalog No.
BA6956
LTGO-33 is a potent and selective voltage-gated sodium channel inhibitor.
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LTGO-33 is a potent and selective inhibitor of voltage-gated sodium channels.LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits more than 600-fold selectivity for human NaV1.1-NaV1.7 and NaV1.9.LTGO-33 is similarly potent for channels in the closed and inactivated conformations, showing state-independent inhibition .LTGO-33 inhibits natural TTX-RNaV1.8 currents in non-human primate and human DRG neurons, thereby reducing action potential discharges.LTGO-33 can be used in pain disorder research.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 467.44 |
| Cas No. | 2834106-06-6 |
| Formula | C21H17F4N3O3S |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |