Toggle Nav
Close
  • Menu
  • Setting

Liraglutide

Catalog No.
B7949
 
Grouped product items
SizePriceStock Qty
1mg
$145.00
In stock
5mg
$580.00
In stock
10mg
$995.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Liraglutide (CAS 204656-20-2) is a peptide-based agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), a G protein-coupled receptor predominantly expressed in pancreatic β cells and vascular endothelial cells. Activation of GLP-1R facilitates glucose-dependent insulin secretion and maintains glucose homeostasis. In endothelial cell studies (C11-STH^20), liraglutide (100 nM) reduced expression of plasminogen activator inhibitor type-1 (PAI-1) and vascular adhesion molecules, mitigating endothelial dysfunction. In ApoE^-/- mice, liraglutide administration (300 μg/kg, twice daily, subcutaneously) increased endothelial nitric oxide synthase (eNOS) and decreased intercellular adhesion molecule-1 (ICAM-1) expression, effects mediated specifically through GLP-1R signaling. These properties make liraglutide valuable for research on endothelial function and vascular complications in diabetic contexts.

Product Citation

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt3751.20
Cas No.204656-20-2
FormulaC172H265N43O51
Solubilityinsoluble in EtOH; insoluble in DMSO; insoluble in H2O
SDFDownload SDF
Canonical SMILESCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Liraglutide

Related Biological Data

Liraglutide