JNJ-10229570
Catalog No.
BA5540
JNJ-10229570 is an antagonist of adrenocortical receptor 1 and adrenocortical receptor 5.
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JNJ-10229570, an antagonist of adrenocortical receptor 1 and adrenocortical receptor 5, inhibits sebaceous gland differentiation and the production of cortical-specific lipids, with values of 270 nM and 200 nM for inhibition of I-NDP-alpha-MSH and MC1R and MC5R binding in human cells, respectively.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 389.47 |
| Cas No. | 524923-88-4 |
| Formula | C22H19N3O2S |
| Solubility | ≥51.6 mg/mL in DMSO; ≥10.22 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (Z)-2,3-bis(2-methoxyphenyl)-N-phenyl-1,2,4-thiadiazol-5(2H)-imine |
| SDF | Download SDF |
| Canonical SMILES | COC1=C(C=CC=C1)C(N(S/2)C3=C(OC)C=CC=C3)=NC2=N\C4=CC=CC=C4 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
