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JB170

Catalog No.
BA3719
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JB170 is a potent and highly specific mediated degradation agent.
Grouped product items
SizePriceStock Qty
1mL(10 mM in DMSO)
$763.00
Ship with 10-15 days
1mg
$196.00
Ship with 10-15 days
5mg
$432.00
Ship with 10-15 days
10mg
$720.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

JB170 is a potent and highly specific mediator of degradation (=28nM) formed by linking Alisertib to the ligand Thalidomide.JB170 binds preferentially to AURORA-A (=193nM) rather than AURORA-B (EC=1.4μM).JB170-mediated S-phase block is caused by AURORA -A depletion.JB170 has a high capacity to inhibit the non-catalytic function of AURORA-A kinase.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt963.36
Cas No.2705844-82-0
FormulaC48H44ClFN8O11
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.