Isomalt
Isomalt (CAS No.: 64519-82-0) is a non-toxic polyol known for its application as a protein stability enhancer in biomedical research, especially showing a moderate stabilizing effect on lactate dehydrogenase (LDH) during lyophilization and excellent stability during storage. Its chemical composition consists of a mixture of 1,6-mannitol glucoside and 1,6-sorbitol glucoside, making it unique among polyols. Although it was initially used as a sweetener in the food industry and as an excipient for pharmaceutical tablets, Isomalt has been developed in the biomedical field for its capability as an excipient. Although specific experimental data are not extensive in some applications, including IC50 or EC50 values, similar polyols have demonstrated utility in the nanomolar to micromolar range. In biochemical assays, Isomalt can be effectively used in cell models or preliminary drug screening as a tool for evaluating protein stability and excipient tolerance, with its concentration typically adjusted according to the experimental framework and objectives. Its mechanism of action is mainly achieved through molecular stabilization, making it a key component in pharmaceutical formulations focused on stability and delivery, without specific biological activity or mechanism of action.
| Physical Appearance | Solid |
| Storage | -20°C |
| M.Wt | 344.31 |
| Cas No. | 64519-82-0 |
| Formula | C12H24O11 |
| Synonyms | Palatinitol |
| Solubility | ≥54.4 mg/mL in DMSO; insoluble in EtOH; ≥52.4 mg/mL in H2O |
| Chemical Name | (2S,3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol |
| Canonical SMILES | O(C[C@H]([C@H]([C@@H](C(CO)O)O)O)O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
