Indole-3-Acetic Acid (sodium salt)

Indole-3-Acetic Acid (sodium salt) (CAS No.: 6505-45-9) is the sodium salt form of indole-3-acetic acid, an endogenous indole-derived metabolite and the principal auxin phytohormone widely distributed across plant and animal systems, where it plays a central role in regulating growth and developmental processes. Functionally, it is closely associated with auxin signaling pathways, modulating cellular activities such as expansion, differentiation, morphogenesis, and organogenesis through interactions with auxin-responsive transcriptional regulators and downstream gene expression programs. In plant models, it acts as a potent growth regulator influencing root formation and shoot development, with biological activity typically observed in the micromolar concentration range depending on experimental context. Emerging evidence indicates that indole-3-acetic acid and its derivatives also exhibit bioactivity in mammalian cells, where they are employed in studies of cell proliferation, differentiation, and intracellular signaling pathways, suggesting potential cross-kingdom relevance of auxin-related mechanisms. As a research tool, this compound is widely used in cell-based assays, plant physiology studies, and exploratory drug discovery efforts aimed at elucidating signaling networks and identifying novel bioactive pathways, with experimental concentrations or dosing regimens varying according to specific model systems and research objectives.