Hydroxy-PEG4-(CH2)2-Boc
Hydroxy-PEG4-(CH2)2-Boc is a linker (ADC linker) commonly used in antibody conjugated drug (ADC) synthesis. The molecular structure contains polyethylene glycol (PEG) segments, which can improve the water solubility and stability of the drug, reduce non-specific binding, and improve pharmacokinetic properties. The Boc protection group at the end can protect the amino or hydroxyl functional groups during the synthesis process, and facilitate the subsequent functional modification. The linker is widely used in the preparation of ADC drugs. By connecting antibodies with cytotoxic drugs, it can achieve targeted drug delivery, reduce toxic side effects and improve therapeutic effect. Hydroxy-PEG4-(CH2)2-Boc has become an important tool molecule in ADC drug development due to its good biocompatibility and flexible structural design.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 322.4 |
| Cas No. | 518044-32-1 |
| Formula | C15H30O7 |
| Solubility | Soluble in DMSO |
| Chemical Name | tert-butyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate |
| SDF | Download SDF |
| Canonical SMILES | O=C(OC(C)(C)C)CCOCCOCCOCCOCCO |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
