Hydroxy-PEG2-(CH2)2-Boc
Catalog No.
A9978
A linker (ADC linker) commonly used to synthesize antibody-coupled active molecules (ADCs)
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Hydroxy-PEG2-(CH2)2-Boc is a linker (ADC linker) commonly used to synthesize antibody-coupled active molecules (ADCs). The molecular structure contains polyethylene glycol (PEG) segments, which can improve the water solubility and stability of the drug, reduce immunogenicity, and improve the pharmacokinetic properties of the drug. The terminal tert-butoxycarbonyl (Boc) protection group protects the amino or hydroxyl functional groups during synthesis, facilitating subsequent coupling reactions. The linker is widely used in the development of ADC drugs. By connecting antibodies with cytotoxic drugs, it can achieve accurate drug delivery, reduce non-specific toxicity, and improve therapeutic efficacy and safety.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 234.29 |
| Cas No. | 133803-81-3 |
| Formula | C11H22O5 |
| Solubility | Soluble in DMSO |
| Chemical Name | tert-butyl 3-(2-(2-hydroxyethoxy)ethoxy)propanoate |
| SDF | Download SDF |
| Canonical SMILES | OCCOCCOCCC(OC(C)(C)C)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
