HQ461
Catalog No.
BA3763
HQ461 is a molecular gel that promotes CDK12-DDB1 interaction to trigger degradation.
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HQ461 is a molecular glue that promotes CDK12-DDB1 interactions to trigger degradation.HQ461-mediated degradation of cyclinK impairs function, leading to decreased substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 345.44 |
Cas No. | 1226443-41-9 |
Formula | C15H15N5OS2 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |