Heptadecanoic Acid
Heptadecanoic Acid (CAS No.: 506-12-7) is an odd-chain saturated fatty acid predominantly identified in dairy fat and widely utilized in biomedical research as both a metabolic biomarker and a functional lipid probe. Classified within the family of odd-chain fatty acids, it has been implicated in the regulation of metabolic and immune-related signaling pathways, with accumulating evidence linking its biological activity to processes underlying coronary heart disease, pre-diabetes, type 2 diabetes, and multiple sclerosis. Mechanistically, heptadecanoic acid has been reported to modulate cellular signaling networks involved in proliferation and survival, exhibiting the capacity to inhibit cell growth and induce apoptosis in vitro, consistent with observed antitumor activity in experimental systems, typically at low micromolar to micromolar concentrations depending on cell type and assay conditions. In addition to its functional roles, it is frequently employed as an internal standard in lipidomic analyses using LC-MS and GC-MS platforms and serves as a reliable biomarker for dietary dairy fat intake in human plasma studies. In preclinical research, it is applied in cell-based assays and animal models to investigate lipid metabolism, inflammatory responses, and disease-associated metabolic alterations, with dosing and exposure parameters tailored to specific experimental objectives.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 270.45 |
| Cas No. | 506-12-7 |
| Formula | C17H34O2 |
| Synonyms | C17:0; FA 17:0; n-Heptadecoic Acid; Heptadecylic Acid; Margaric Acid; NSC 3743 |
| Solubility | insoluble in EtOH; ≥1.36 mg/mL in H2O with gentle warming and ultrasonic; ≥29.7 mg/mL in DMSO with ultrasonic |
| Chemical Name | heptadecanoic acid |
| Canonical SMILES | CCCCCCCCCCCCCCCCC/C(O)=N/[C@@]([C@@](O)([H])/C([H])=C([H])/CCCCCCCCCCCCC)([H])CO[C@@]1([H])[C@@](O)([H])[C@](O)([H])[C@@](O[C@@]2([H])[C@@](O)([H])[C@](O[C@]3(C(O)=O)C[C@@](O)([H])[C@](/N=C([O-])/C)([H])[C@](O3)([H])[C@@](O)([H])[C@@](O)([H])CO)([H])[C@]( |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |