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H3B-8800

Catalog No.
BA2960
H3B-8800 is a potent orally active SF3B splicing modulator.
Grouped product items
SizePriceStock Qty
1mg
$261.00
In stock
5mg
$711.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

H3B-8800 is a potent orally active SF3B splicing modulator.H3B-8800 interacts directly with the SF3b complex and shows anticancer activity.H3B-8800 has the potential to study mutant acute myeloid leukemia (AML).

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt555.71
Cas No.1825302-42-8
FormulaC31H45N3O6
Solubility≥28.35 mg/mL in DMSO with ultrasonic; ≥50.9 mg/mL in EtOH; insoluble in H2O
Chemical Name(2S,3S,6S,7R,10R,E)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-((R,2E,4E)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl)oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate
SDFDownload SDF
Canonical SMILESC[C@@H](/C=C/[C@H](OC(N1CCN(C)CC1)=O)[C@](C)(O)CC[C@@H](O)C2)[C@H](OC2=O)/C(C)=C/C=C/[C@@H](C)C3=NC=CC=C3
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

H3B-8800