H3B-6527
Catalog No.
BA8933
H3B-6527 is an orally active, highly selective and covalent inhibitor <1.2 nM.
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H3B-6527 is an orally active, highly selective and covalent inhibitor at <1.2 nM.H3B-6527 inhibits FGFR1-3 at 320, 1290 and 1060 nM, respectively.H3B-6527 has good anticancer activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 629.54 |
| Cas No. | 1702259-66-2 |
| Formula | C29H34Cl2N8O4 |
| Solubility | ≥12.65 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O |
| Chemical Name | N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide |
| Canonical SMILES | O=C(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C)C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)=C3)C=C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
