H-Phe-Phe-OH
H-Phe-Phe-OH (CAS No.: 2577-40-4) is a dipeptide composed of two phenylalanine residues, an essential aromatic amino acid that serves as a precursor to tyrosine, and is widely utilized as a biochemical tool in peptide science and molecular pharmacology research. Owing to its simple yet structurally defined aromatic backbone, this compound is frequently investigated for its capacity to modulate protein–protein interactions, influence enzyme activity, and interfere with intracellular signaling pathways associated with cellular regulation. Studies suggest that dipeptides of this class can affect biochemical processes through mechanisms such as competitive binding or conformational modulation of target proteins, typically exhibiting activity in the nanomolar to micromolar range depending on the experimental system. H-Phe-Phe-OH is therefore commonly applied in in vitro assays to explore peptide-mediated signaling, enzyme kinetics, and transport processes, as well as in cell-based models to evaluate its impact on metabolic or regulatory pathways. In drug discovery settings, it may serve as a reference compound or structural motif for the design of peptide-based modulators, with experimental concentrations or dosing regimens varying according to specific assay conditions and research objectives.
| Physical Appearance | Solid |
| Storage | -20°C |
| M.Wt | 312.36 |
| Cas No. | 2577-40-4 |
| Formula | C18H20N2O3 |
| Solubility | Insoluble in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | L-phenylalanyl-L-phenylalanine |
| Canonical SMILES | O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)N)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |







